Drug Profile


Alternative Names: ALT 11; Aminoguanidine hydrochloride

Latest Information Update: 22 Dec 2003

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At a glance

  • Originator Nonindustrial source; Rockefeller University
  • Developer Alteon; Gamida; Nonindustrial source
  • Class Guanidines; Hydrazines; Small molecules
  • Mechanism of Action Advanced glycosylation end product inhibitors; Nitric oxide synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Atopic dermatitis; Coronary disorders; Dermatitis; Diabetic complications; Diabetic nephropathies; Stroke; Transplant rejection

Most Recent Events

  • 22 Dec 2003 Discontinued - Preclinical for Coronary disorders in USA (PO)
  • 22 Dec 2003 Discontinued - Preclinical for Stroke (IV)
  • 22 Dec 2003 Discontinued - Preclinical for Transplant rejection in USA (unspecified route)
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