Drug Profile


Alternative Names: Kvaterin; MET-88; Mildronate; Quaterin

Latest Information Update: 04 Jul 2016

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At a glance

  • Originator Latvian Institute of Organic Synthesis
  • Developer Grindeks; Taiho Pharmaceutical
  • Class Adjuvants; Antiarrhythmics; Cardiotonics; Ischaemic heart disorder therapies; Methylhydrazines; Propionates; Small molecules; Vasodilators
  • Mechanism of Action Gamma-butyrobetaine dioxygenase inhibitors; Partial fatty acid oxidation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Heart failure; Ischaemic heart disorders
  • No development reported Angina pectoris; Arrhythmias

Most Recent Events

  • 04 Jul 2016 Phase III development is ongoing in China
  • 30 May 2014 Phase-III clinical trials in Heart failure in China (IV)
  • 30 May 2014 Phase-III clinical trials in Heart failure in China (PO)
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