Drug Profile


Alternative Names: BMY 13105; Bucindolol hydrochloride; Gencaro; MJ 13105; MJ 131051

Latest Information Update: 24 Aug 2017

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer ARCA biopharma Inc; Medtronic
  • Class Heart failure therapies; Propanolamines; Small molecules
  • Mechanism of Action Beta 1 adrenergic receptor antagonists; Beta 2 adrenergic receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Atrial fibrillation
  • Discontinued Heart failure; Myocardial infarction

Most Recent Events

  • 26 May 2017 Phase-II/III clinical trials in Atrial fibrillation (Recurrent, Prevention) in Bulgaria (PO) (EudraCT2016-000302-12)
  • 06 Oct 2016 Phase-II/III clinical trials in Atrial fibrillation (Prevention, Recurrent) in Hungary (PO) (NCT01970501)
  • 13 Jul 2016 Phase-II/III clinical trials in Atrial fibrillation (Prevention, Recurrent) in Poland (PO) (EudraCT2016-000302-12)
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