Drug Profile


Alternative Names: AT 877; Chuanwei; Eril; Eril Injection S; HA 1077

Latest Information Update: 22 Apr 2016

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At a glance

  • Originator Asahi Kasei
  • Developer Asahi Kasei; Asahi Kasei Pharma Corp; Eisai Co Ltd; Tianjin Chase Sun Pharmaceutical
  • Class Amines; Anti-ischaemics; Ischaemic heart disorder therapies; Isoquinolines; Small molecules; Sulfonamides
  • Mechanism of Action Calcium channel antagonists; Protein kinase C inhibitors; Rho-associated kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Cerebral ischaemia; Cerebral vasospasm
  • Clinical Phase Unknown Pulmonary arterial hypertension
  • Discontinued Angina pectoris; Atherosclerosis; HIV-1 infections; Intracranial thrombosis

Most Recent Events

  • 27 Dec 2013 Discontinued - Preclinical for Cerebral ischaemia in South Korea (IV)
  • 01 Jul 2013 Launched for Cerebral vasospasm in China (IV)
  • 31 May 2013 Phase-II clinical trials in Pulmonary arterial hypertension in Japan (PO)
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