Iloprost

Drug Profile

Iloprost

Alternative Names: BAYQ 6256; Breelib; Ciloprost; E-1030; Endoprost; Ilocit; Iloderm; Ilomedin; Ilomedine; Iloprost inhalation solution; Iloprost power 15 (Ventavis®) - Actelion; Iloprost trometamol; Isoiloprost; SH-401; Ventavis; VR-876 - Vectura; ZK-36375

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Bayer HealthCare Pharmaceuticals
  • Developer Actelion Pharmaceuticals; Bayer HealthCare Pharmaceuticals
  • Class Alkynes; Anti-ischaemics; Antiplatelets; Peripheral vasodilators; Prostaglandins; Small molecules
  • Mechanism of Action Epoprostenol agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary hypertension; Pulmonary arterial hypertension
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Arterial occlusive disorders; Pulmonary arterial hypertension; Raynaud's disease; Thromboangiitis obliterans
  • Discontinued Pulmonary hypertension

Most Recent Events

  • 16 Jun 2017 Actelion Pharmaceuticals has been acquired by Janssen Pharmaceuticals
  • 22 Dec 2016 Bayer completed EU regulatory procedure for VR 876 (breath activated nebuliser)
  • 01 Dec 2016 Bayer completes the IBUKI trial in Pulmonary arterial hypertension in Japan (Inhalation) (NCT01469169)
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