Drug Profile


Alternative Names: ATL-1251; AZM 112; BRL-24924

Latest Information Update: 09 Feb 2017

Price : $50

At a glance

  • Originator GlaxoSmithKline
  • Developer Alizyme; EndoLogic; GlaxoSmithKline
  • Class Benzamides; Gastrokinetics; Heterocyclic bicyclo compounds; Irritable bowel syndrome therapies; Small molecules
  • Mechanism of Action Serotonin 3 receptor antagonists; Serotonin 4 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Gastro-oesophageal reflux; Gastroparesis; Irritable bowel syndrome

Most Recent Events

  • 04 Jan 2017 EndoLogic acquires worldwide rights to renzapride for development in gastroparesis
  • 04 Jan 2017 EndoLogic plans a phase II trial for Gastroparesis in USA
  • 23 Apr 2008 Discontinued - Phase-III for Irritable bowel syndrome in USA (PO)
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