Drug Profile


Alternative Names: ATL-1251; AZM 112; BRL-24924; Renzapride hydrochloride

Latest Information Update: 18 Aug 2017

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At a glance

  • Originator GlaxoSmithKline
  • Developer Alizyme; EndoLogic; GlaxoSmithKline
  • Class Benzamides; Gastrokinetics; Heterocyclic bicyclo compounds; Irritable bowel syndrome therapies; Small molecules
  • Mechanism of Action Serotonin 3 receptor antagonists; Serotonin 4 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Gastroparesis
  • Discontinued Gastro-oesophageal reflux; Irritable bowel syndrome

Most Recent Events

  • 18 Aug 2017 EndoLogic is seeking funds for development of renzapride as of 10 Aug 2017.
  • 09 Aug 2017 EndoLogic announces intention to submit an IND application to US FDA for Gatroparesis in the fourth quarter of 2017
  • 04 Jan 2017 EndoLogic plans a phase II trial for Gastroparesis in USA
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