Drug Profile


Alternative Names: Ecopipam HCl; PSYRX 101; SCH-39166

Latest Information Update: 20 Jan 2017

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At a glance

  • Originator Schering-Plough
  • Developer Psyadon Pharmaceuticals; Schering-Plough; University of California Riverside School of Medicine
  • Class Antipsychotics; Benzazepines; Small molecules
  • Mechanism of Action Dopamine D1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Lesch-Nyhan syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Lesch-Nyhan syndrome
  • Phase II Gilles de la Tourette's syndrome
  • Preclinical Speech disorders
  • No development reported Gambling
  • Discontinued Cocaine abuse; Obesity; Schizophrenia

Most Recent Events

  • 12 Jul 2017 Restless Legs Syndrome Foundation plans a phase I/II trial for Restless legs syndrome in USA (NCT03218969) in July 2017
  • 17 Jan 2017 Psyadon completes enrolment in its phase II trial for Gilles de la Tourette's syndrome (In adolescent, In children) in USA
  • 20 Sep 2016 Preclinical trials in Speech disorders in USA before September 2016 (PO)
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