Drug Profile


Alternative Names: AF 102B; Cevimeline hydrochloride; Evoxac; FKS 508; Saligren; SND 5088; SNI 2011; SNK 508

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Israel Institute for Biological Research
  • Developer Daiichi Sankyo Company; Nippon Kayaku; SnowBrand Pharmaceuticals
  • Class Quinuclidines; Small molecules; Thiophenes
  • Mechanism of Action Muscarinic M1 receptor agonists; Muscarinic M3 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Marketed Xerostomia
  • Discontinued Alzheimer's disease

Most Recent Events

  • 15 Mar 2016 Biomarkers information updated
  • 09 Oct 2012 Authorised generic equivalent available in USA
  • 27 Aug 2007 No development reported - Clinical-Phase-Unknown for Dry eyes in USA (unspecified route)
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