Drug Profile


Alternative Names: Boxeprazine; GBR-12909

Latest Information Update: 19 Jan 2017

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At a glance

  • Originator Gist-Brocades
  • Developer Laguna Pharmaceuticals; Novo Nordisk
  • Class Antidepressants; Antiparkinsonians; Piperazines; Small molecules
  • Mechanism of Action Dopamine plasma membrane transport protein antagonists; Dopamine uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Atrial fibrillation; Cocaine abuse; Major depressive disorder; Parkinson's disease; Peptic ulcer

Most Recent Events

  • 04 Dec 2015 Discontinued - Phase-III for Atrial fibrillation in USA, Bulgaria, Hungary, Israel, Netherlands, Poland and Russia (PO)
  • 01 Sep 2015 Phase-III clinical trials in Atrial fibrillation in USA, Russia, Israel, Bulgaria, Hungary (PO)
  • 06 Jun 2015 Laguna Pharmaceuticals plans a phase III trial in Atrial fibrillation in USA (NCT02454283)
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