Drug Profile


Alternative Names: Bipenquinate; Brequinar sodium; DUP 785; NSC 368390; NSC 369390

Latest Information Update: 17 Jan 2008

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At a glance

  • Originator Bristol-Myers Squibb
  • Class Biphenyl compounds
  • Mechanism of Action Dihydroorotate dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Cancer; Cytomegalovirus infections; Transplant rejection

Most Recent Events

  • 18 Dec 1998 A study has been added to the Transplant rejection pharmacodynamics section
  • 16 Dec 1998 Phase-II clinical trials for Transplant rejection in USA (PO)
  • 16 Dec 1998 A study in transplant patients has been added to the pharmacokinetics section
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