Drug Profile


Alternative Names: Ethiofos; Ethyol; Gammaphos; NSC 296961; WR 2721; YM 08310

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Southern Research Institute
  • Developer MedImmune Oncology
  • Class Chemoprotectants; Organothiophosphorus compounds; Small molecules
  • Mechanism of Action Oxygen radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Radioprotection; Chemoprotection; Myelodysplastic syndromes
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Chemoprotection; Radioprotection
  • Discontinued Myelodysplastic syndromes

Most Recent Events

  • 10 May 2016 Clinigen and Cumberland Pharmaceuticals enter into an agreement for commercialisation of amifostine in USA
  • 20 Aug 2014 Clinigen acquires global right to amifostine from AstraZeneca (MedImmune)
  • 29 Jan 2008 Discontinued - Clinical-Phase-Unknown for Radioprotection in USA (SC)
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