Drug Profile


Alternative Names: AT 125; NSC 163501; U 42126

Latest Information Update: 19 Jan 2006

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At a glance

  • Originator Pfizer
  • Class Antineoplastics
  • Mechanism of Action Enzyme inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued CNS cancer; Diabetes mellitus; Leukaemia; Liver cancer; Non-small cell lung cancer; Ovarian cancer; Solid tumours

Most Recent Events

  • 18 Jan 2006 Discontinued - Phase-I for Non-small cell lung cancer in Canada (IV)
  • 18 Jan 2006 Discontinued - Phase-I for Solid tumours in Canada (IV)
  • 18 Jan 2006 Discontinued - Phase-II for CNS cancer in USA (IV)
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