Drug Profile


Alternative Names: EO 9; EOquin; Neoquin; NOR 701; NSC 382456; Qapzola

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator Spectrum Pharmaceuticals
  • Developer Handok Inc; Nippon Kayaku; Spectrum Pharmaceuticals
  • Class Aziridines; Cytostatic antibiotics; Indolequinones
  • Mechanism of Action Alkylating agents; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Bladder cancer

Most Recent Events

  • 08 Mar 2017 Spectrum Pharmaceuticals plans a phase III trial for Bladder cancer (Adjuvant therapy) in USA
  • 01 Feb 2017 Spectrum Pharmaceuticals and US FDA agree on a Special Protocol Assessment (SPA) for a phase III trial of apaziquone for Bladder cancer
  • 12 Dec 2016 Spectrum Pharmaceuticals terminates a phase III trial in Bladder cancer (non-invasive disease) in USA and Canada due to business reasons (NCT01410565)
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