Drug Profile


Alternative Names: 1 OHP; 1670 RB7; Dacotin; Dacplat; Eloxatin; Elplat; NSC 266046; Oxalatoplatin; Oxalatoplatinum; RP 54780; SR 96669

Latest Information Update: 13 Oct 2017

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At a glance

  • Originator Nagoya University
  • Developer Alliance for Clinical Trials in Oncology; Beth Israel Deaconess Medical Center; Chugai Pharmaceutical; Dana-Farber Cancer Institute; Debiopharm; Dr Reddys Laboratories; Pfizer; Sanofi; University of Southern California; University of Texas M. D. Anderson Cancer Center; Yakult Honsha
  • Class Antineoplastics; Platinum complexes; Small molecules
  • Mechanism of Action DNA cross linking agents; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Colorectal cancer
  • Registered Gastric cancer; Hepatocellular carcinoma; Pancreatic cancer
  • Phase II Germ cell and embryonal neoplasms; Intestinal cancer; Oesophageal cancer; Ovarian cancer; Testicular cancer; Uterine cancer
  • Discontinued Acute myeloid leukaemia; Breast cancer; Diffuse large B cell lymphoma; Myelodysplastic syndromes; Nasopharyngeal cancer; Non-small cell lung cancer

Most Recent Events

  • 01 Sep 2017 Phase-II clinical trials in Gastric cancer (Combination therapy, Late-stage disease, Metastatic disease) in Japan (IV) (UMIN000028749)
  • 19 Jul 2016 Yakult initiates enrolment in a phase II trial for Gastric cancer (Combination therapy, Late-stage disease, Metastatic disease) in Japan (UMIN000022450)
  • 04 Mar 2016 Debiopharm has patent protection for oxaliplatin in Japan
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