Deferiprone

Drug Profile

Deferiprone

Alternative Names: CGP 37391; CMX 001 - CorMedix; CP 020; CP 20; CRMD-001; Ferriprox; Ferriprox Oral Solution; Kelfer; L1

Latest Information Update: 28 Nov 2017

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At a glance

  • Originator Royal Free and University College Medical School
  • Developer Apotex; Centre Hospitalier Univeristaire De Lille; CorMedix
  • Class Antianaemics; Antineoplastics; Antirheumatics; Pyridones; Small molecules
  • Mechanism of Action Chelating agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Iron overload
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Iron overload
  • Phase III Pantothenate kinase-associated neurodegeneration
  • Phase II Amyotrophic lateral sclerosis; Parkinson's disease
  • Phase I HIV infections
  • No development reported Friedreich's ataxia
  • Discontinued Kidney disorders

Most Recent Events

  • 11 Jan 2017 ApoPharma completes a phase III trial in Pantothenate Kinase Associated Neurodegeneration in Italy, Germany, USA and United Kingdom (PO) (NCT01741532)
  • 01 Dec 2016 ApoPharma completes the phase II trial in Amyotrophic lateral sclerosis in France (PO) (NCT02164253)
  • 05 Aug 2016 Phase-II clinical trials in Parkinson's disease (Early-stage disease, Treatment-experienced) in USA (PO, Controlled-release) (NCT02728843)
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