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Prulifloxacin - Nippon Shinyaku

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Drug Profile

Prulifloxacin - Nippon Shinyaku

Alternative Names: AF 3012; NAD-441A; NM441; OPT-99; PrulifloxacinA brs; Pruvel; Quisnon; Sword; Sword 100; Unidrox

Latest Information Update: 14 Nov 2018

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At a glance

  • Originator Nippon Shinyaku
  • Developer Angelini Group; Cubist Pharmaceuticals; Lee's Pharmaceutical; Merck & Co; Nippon Shinyaku; Optimer Pharmaceuticals
  • Class Antibacterials; Dioxolanes; Fluoroquinolones; Piperazines; Quinolones; Small molecules
  • Mechanism of Action Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute exacerbations of chronic bronchitis; Bacterial infections; Gram-negative infections; Gram-positive infections; Pneumonia; Respiratory tract infections; Urinary tract infections
  • Phase III Prostatitis; Traveller's diarrhoea

Most Recent Events

  • 14 Nov 2018 Launched for Acute exacerbations of chronic bronchitis in China (PO) prior to November 2018 (Lees Pharmaceutical Holdings website, November 2018)
  • 01 Jul 2015 Lees Pharmaceutical completes a phase III trial in Urinary tract infections in China (NCT02439632)
  • 13 May 2015 Prulifloxacin is still in phase-III development for Prostatitis, Traveller's diarrhoea and Acute exacerbations of chronic bronchitis in Italy
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