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Naftopidil - Asahi Kasei Pharma

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Drug Profile

Naftopidil - Asahi Kasei Pharma

Alternative Names: Avishot; BM-15275; Eapidil; FLIVAS; Flivas; KT-611; Naphtopidil

Latest Information Update: 13 Nov 2025

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At a glance

  • Originator Roche
  • Developer Asahi Kasei; Asahi Kasei Pharma Corp; Dong-A ST; MSD KK
  • Class Antihypertensives; Naphthalenes; Piperazines; Small molecules
  • Mechanism of Action 5-HT1A serotonin receptor agonists; Alpha 1 adrenergic receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Benign prostatic hyperplasia
  • Phase III Postoperative pain
  • Discontinued Neurogenic bladder; Urinary calculi

Most Recent Events

  • 30 Jun 2021 Launched for Benign prostatic hyperplasia in China (PO) (Asahi Kasei Pharma Corp website, November 2025)
  • 19 Jan 2018 No development reported - Phase-III for Urinary calculi in South Korea (PO)
  • 01 Aug 2015 Dong-A ST completes a phase III trial in Urinary calculi in South Korea (NCT01952314)

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