Drug Profile


Alternative Names: BRN 6848330; CCRIS 6729; DM 9384; DMPPA; DN-9384; DZL-221; HL-0812; HPI-001; Motiva; Translon

Latest Information Update: 27 Jan 2017

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At a glance

  • Originator Daiichi Sankyo Company
  • Developer Daiichi Sankyo Company; Neuren Pharmaceuticals
  • Class Acetamides; Neuroprotectants; Nootropics; Pyrrolidinones; Small molecules
  • Mechanism of Action Calcium channel agonists; GABA receptor agonists; Nicotinic receptor agonists; NMDA receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Epilepsy
  • Discontinued Dementia; Major depressive disorder

Most Recent Events

  • 15 Mar 2011 Phase-II development is ongoing in US, Australia and Canada for Depression in post-stroke patients
  • 08 Jun 2010 Clinical development is ongoing
  • 12 Mar 2008 Phase-II clinical trials in Depression in USA (PO)
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