Drug Profile


Alternative Names: BCI-540; MKC-231

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Mitsubishi Chemical
  • Developer BrainCells; Mitsubishi Chemical; Takeda
  • Class Neuroprotectants; Nootropics; Pyrrolidinones; Quinolines; Small molecules
  • Mechanism of Action AMPA receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Alzheimer's disease; Anxiety disorders; Major depressive disorder

Most Recent Events

  • 26 Jun 2012 Coluracetam is available for licensing as of 26 Jun 2012.
  • 15 May 2012 Mitsubishe Tanabe Pharma terminates a licence agreement for coluracetam (Mitsubishi Tanabe Pharma May 8 2012 pipeline)
  • 16 Jun 2010 Safety and efficacy data from a phase IIa trial in Major depressive disorder with anxiety released by BrainCells
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