Letrozole

Drug Profile

Letrozole

Alternative Names: CGP 20267; CGS 20267; Femara; Letzazole

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Novartis
  • Developer National Cancer Institute (USA); Novartis
  • Class Antineoplastics; Nitriles; Small molecules; Triazoles
  • Mechanism of Action Aromatase inhibitors; Estrogen receptor antagonists; Estrogen receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Breast cancer
  • Phase II Endometrial cancer; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Discontinued Delayed puberty; Endometriosis; Female infertility

Most Recent Events

  • 21 Feb 2017 University of Colorado plans a phase I/II trial for Breast cancer (Combination therapy, Metastatic disease, Inoperable/Unresectable) in USA (NCT03054363)
  • 10 Jan 2017 Novartis completes a phase III trial in Breast cancer (Early-stage disease, Combination therapy) in Netherlands, Belgium, Spain, Slovenia, Germany, United Kingdom, Italy, Portugal (PO) (NCT00433589)
  • 02 Jan 2017 M.D. Anderson Cancer Center and Novartis plan a phase II trial for Endometrial cancer (Recurrent, Combination therapy, Second-line therapy or greater, Late-stage disease) in USA (NCT03008408)
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