Drug Profile


Alternative Names: 1580RB; Bestatin; NK 421

Latest Information Update: 12 Jan 2017

Price : $50

At a glance

  • Originator Institute of Microbial Chemistry
  • Developer Eiger BioPharmaceuticals, Inc.; Nippon Kayaku
  • Class Antineoplastics; Branched-chain amino acids; Dipeptides; Essential amino acids
  • Mechanism of Action Aminopeptidase B inhibitors; Immunostimulants; Leukotriene A4 hydrolase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary arterial hypertension
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Cancer
  • Phase II Lymphoedema; Pulmonary arterial hypertension
  • Preclinical Inflammation
  • Discontinued HIV infections

Most Recent Events

  • 01 Oct 2016 Eiger BioPharmaceuticals initiates enrolment in the extension phase II LIBERTY2 trial for Pulmonary arterial hypertension in USA (PO) (NCT02736149)
  • 23 Jun 2016 Phase-II clinical trials in Lymphoedema (In adults) in USA (PO) (NCT02700529)
  • 07 Apr 2016 Eiger BioPharmaceuticals plans the extension phase II LIBERTY2 trial for Pulmonary arterial hypertension in USA (PO) (NCT02736149)
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