Drug Profile


Alternative Names: DasKloster 1000; DasKloster 1000-01; DasKloster 1000-02; DasKloster 1000-03; DasKloster 1000-04; DK 1000; Vasoactive intestinal peptide

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator mondoBIOTECH
  • Developer Lung Rx; mondoBIOTECH; RELIEF THERAPEUTICS Holding
  • Class Gastrointestinal hormones; Neuropeptides; Peptide hormones
  • Mechanism of Action Vasoactive intestinal peptide receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary hypertension; Adult respiratory distress syndrome; Pulmonary sarcoidosis; Acute lung injury; Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes
  • Available For Licensing Yes - Acute lung injury; Adult respiratory distress syndrome; Chronic obstructive pulmonary disease; Pulmonary hypertension; Pulmonary sarcoidosis

Highest Development Phases

  • Phase III Pulmonary sarcoidosis
  • Phase II Adult respiratory distress syndrome
  • Discontinued Idiopathic pulmonary fibrosis; Pulmonary arterial hypertension

Most Recent Events

  • 18 Jul 2016 Phase-II clinical trials in Adult respiratory distress syndrome in Switzerland (Parenteral)
  • 18 Jul 2016 Phase-III for Pulmonary sarcoidosis in European Union (Inhalation)
  • 21 Apr 2016 THERAMetrics enter into a binding agreement to combine with Relief Therapeutics
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