Drug Profile


Alternative Names: Aggrastat; L 462; L 700462; MK 0383; MK 383; Tirofiban HCl

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator Merck & Co
  • Developer 4P Therapeutics; Cardiome Pharma; Eddingpharm; Medicure
  • Class Antiplatelets; Aromatic amino acids; Ischaemic heart disorder therapies
  • Mechanism of Action GPIIb-IIIa antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Acute coronary syndromes; Arterial thrombosis; Myocardial infarction; Unstable angina pectoris
  • No development reported Coronary artery restenosis

Most Recent Events

  • 16 Feb 2017 Tirofiban is available for licensing as of 16 Feb 2017. http://cardiome.ca/partners/ (Cardiome Pharma pipeline, February 2017)
  • 14 Oct 2016 Cardiome Pharma re-launches tirofiban for unstable Angina pectoris in Canada
  • 01 Sep 2016 USFDA approves bolus vial as new product format for administration of tirofiban in treatment of acute coronary syndrome in USA
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