Drug Profile


Alternative Names: BMS 182751; BMY 45594; JM-216; Orplatna

Latest Information Update: 08 Dec 2016

Price : $50

At a glance

  • Originator Bristol-Myers Squibb; Johnson Matthey; The Institute of Cancer Research
  • Developer Agennix AG; Yakult Honsha
  • Class Antineoplastics; Cyclohexylamines; Platinum complexes
  • Mechanism of Action DNA cross linking agents; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Squamous cell cancer
  • Phase I Prostate cancer
  • Discontinued Breast cancer; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 25 May 2016 Yakult Honsha completes a phase-I clinical trial in Prostate cancer (Combination therapy, Hormone refractory, Second-line therapy or greater) in Japan (JapicCTI-080634) prior to May 2016
  • 31 May 2012 Discontinued - Phase-I for Solid tumours (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)
  • 31 May 2012 Discontinued - Phase-II for Breast cancer in USA (PO)
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