Drug Profile


Alternative Names: FMdc; KW 2331; MDL 101731

Latest Information Update: 22 Mar 2004

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At a glance

  • Originator Aventis
  • Class Antineoplastics; Nucleosides; Small molecules
  • Mechanism of Action Ribonucleoside triphosphate reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Colorectal cancer; Non-small cell lung cancer; Oesophageal cancer; Solid tumours; Viral infections

Most Recent Events

  • 22 Mar 2004 Discontinued - Phase-I for Solid tumours in Japan (IV)
  • 22 Mar 2004 Discontinued - Phase-I for Solid tumours in USA (IV)
  • 22 Mar 2004 Discontinued - Phase-II for Acute myeloid leukaemia in USA (IV)
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