Drug Profile


Alternative Names: Methyl-G; Methyl-GAG; MGBG; Mitoguazone dihydrochloride; NSC 32946; Zyrkamine

Latest Information Update: 13 Nov 1998

Price : *
* Final gross price and currency may vary according to local VAT and billing address.
* Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase. A link to download a PDF version of the drug profile will be included in your email receipt. Adis is an information provider. We do not sell or distribute the pharmaceutical compounds written about in this database.

At a glance

  • Originator Cancer Therapy and Research Center
  • Class Antineoplastics; Guanidines
  • Mechanism of Action Adenosylmethionine decarboxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Non-Hodgkin's lymphoma; Non-small cell lung cancer; Pancreatic cancer; Prostate cancer

Most Recent Events

  • 13 Nov 1998 Discontinued-Clinical for Prostate cancer in USA (IV)
  • 13 Nov 1998 Discontinued-II for Non-small cell lung cancer in USA (IV)
  • 13 Nov 1998 Discontinued-preregistration for Non-Hodgkin's lymphoma in USA (IV)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at so we can help.

Back to top