AS 101

Drug Profile

AS 101

Alternative Names: AS101; CB-06-02; IVAX-Q-101; IVX-Q-101; Ossirene; WAX-120337

Latest Information Update: 11 Dec 2017

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At a glance

  • Originator Bar-Ilan University
  • Developer BioMAS; Cassiopea
  • Class Antineoplastics; Antipsoriatics; Antivirals; Nitrogen compounds; Organometallic compounds; Small molecules
  • Mechanism of Action Integrin alpha4beta1 antagonists; Integrin alphaVbeta3 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Age-related macular degeneration; Genital warts
  • Preclinical Female infertility; Male infertility
  • Discontinued Acute myeloid leukaemia; Atopic dermatitis; Chemotherapy-induced damage; HIV infections; Myelodysplastic syndromes; Neurological disorders; Psoriasis; Thrombocytopenia

Most Recent Events

  • 07 Dec 2017 BioMAS completes enrolment in its phase II trial for Genital warts in Israel (NCT01943630)
  • 11 Jul 2017 Feramda plans a phase I/II trial for Wet age related macular degeneration (PO, Solution) (NCT03216538)
  • 07 Aug 2015 Phase-II development is ongoing for Genital warts in Israel
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