Abatacept

Drug Profile

Abatacept

Alternative Names: BMS-188667; BMS-188667SC; CTLA4-Ig; hCTLA4-Ig-Bristol-Myers-Squibb; ONO-4164; ONO-4164-IV; ONO-4164-SC; Orencia; Orencia IV; Orencia SC

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Bristol-Myers Squibb; National Institute of Allergy and Infectious Diseases; Ono Pharmaceutical; Simcere Pharmaceutical Group; University Medical Center Groningen; University of Michigan
  • Class Antipsoriatics; Antirheumatics; Eye disorder therapies; Immunoconjugates; Immunoglobulin fusion proteins
  • Mechanism of Action T cell activation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Juvenile rheumatoid arthritis; Psoriatic arthritis; Rheumatoid arthritis
  • Phase III Lupus nephritis; Myositis; Sjogren's syndrome
  • Phase II Diffuse scleroderma; Nephrotic syndrome
  • Preclinical Inflammation
  • No development reported Ulcerative colitis
  • Discontinued Crohn's disease; Graft-versus-host disease; Multiple sclerosis; Psoriasis; Systemic lupus erythematosus; Transplant rejection; Xenotransplant rejection

Most Recent Events

  • 26 Jul 2017 Launched for Psoriatic arthritis (Combination therapy, Treatment-resistant) in Norway, Greece, United Kingdom, Sweden, Spain, Portugal, Poland, Netherlands, Italy, Ireland, Hungary, Germany, France, Finland, Czech Republic, Belgium, Austria, Denmark (SC)
  • 26 Jul 2017 Launched for Psoriatic arthritis (Monotherapy, Treatment-resistant) in Austria, Belgium, Czech Republic, Denmark, Finland, France, Germany, Hungary, Ireland, Italy, Netherlands, Poland, Portugal, Spain, Sweden, United Kingdom, Greece, Norway (SC)
  • 26 Jul 2017 Registered for Psoriatic arthritis (Combination therapy, Treatment-resistant) in Liechtenstein, Iceland, Norway, European Union (SC)
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