Drug Profile


Alternative Names: 25.3; 25.3 monoclonal antibody; Anti-CD11a monoclonal antibody 25.3; Anti-LFA-1 monoclonal antibody; Antilfa

Latest Information Update: 22 Dec 2016

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At a glance

  • Originator Immunotech
  • Developer Immunotech; Sanofi Genzyme
  • Class Monoclonal antibodies
  • Mechanism of Action CD11a antigen antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Graft-versus-host disease; Renal transplant rejection
  • Discontinued Delayed graft function

Most Recent Events

  • 08 Apr 2011 Genzyme Corporation has been acquired by sanofi-aventis
  • 08 May 2003 Discontinued - Preclinical for Diabetes mellitus in Japan (Intraperitoneal)
  • 13 Dec 2000 SangStat has discontinued development of odulimomab for the transplant indication in Europe and North America
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