Glufosfamide

Drug Profile

Glufosfamide

Alternative Names: Beta-D-Glc-IPM; D 19575; β-D-Glc-IPM

Latest Information Update: 11 May 2016

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At a glance

  • Originator Baxter Oncology; German Cancer Research Center
  • Developer Baxter Oncology; Eleison Pharmaceuticals; MediBIC; Threshold Pharmaceuticals
  • Class Antineoplastics; Phosphoramide mustards; Small molecules
  • Mechanism of Action Alkylating agents; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Pancreatic cancer
  • Phase I Solid tumours
  • Discontinued Ovarian cancer; Small cell lung cancer; Soft tissue sarcoma

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 05 May 2016 Phase-III clinical trials in Pancreatic cancer (metastatic disease, Second-line therapy or greater) in China (IV)
  • 05 May 2016 Eleison Pharmaceuticals receives approval from the China Food and Drug Administration (CFDA) to enrol patients in China for a phase III trial in Pancreatic cancer
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