Drug Profile


Alternative Names: Algeril; BAY 4503; Dirame; Propiram fumarate

Latest Information Update: 09 Aug 2002

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At a glance

  • Originator Bayer
  • Developer Shire Pharmaceuticals Group
  • Class Non-opioid analgesics; Pyridines; Small molecules
  • Mechanism of Action Opioid mu receptor agonists; Opioid mu receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Musculoskeletal pain; Postoperative pain

Most Recent Events

  • 09 Aug 2002 Discontinued - Phase-III for Musculoskeletal pain in United Kingdom (PO)
  • 09 Aug 2002 Discontinued - Phase-III for Musculoskeletal pain in USA (PO)
  • 09 Aug 2002 Discontinued - Phase-III for Postoperative pain in United Kingdom (PO)
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