Drug Profile


Alternative Names: LY 293558; NGX 424

Latest Information Update: 14 Nov 2016

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At a glance

  • Originator Eli Lilly; Johns Hopkins University
  • Developer Raptor Pharmaceutical Corp
  • Class Analgesics; Antimigraines; Isoquinolines; Tetrazoles
  • Mechanism of Action AMPA receptor antagonists; Kainic acid receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Migraine; Thrombosis

Highest Development Phases

  • Discontinued Migraine; Neuromuscular disorders; Thrombosis

Most Recent Events

  • 12 Aug 2014 Discontinued - Phase-I for Neuromuscular disorders in USA (SC)
  • 12 Aug 2014 Discontinued - Phase-I for Thrombosis (In volunteers) in USA (IV)
  • 12 Aug 2014 Discontinued - Phase-II for Migraine in USA (SC)
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