Dibotermin alfa - Medtronic

Drug Profile

Dibotermin alfa - Medtronic

Alternative Names: Amplify™ rhBMP-2 Matrix; Bone morphogenetic protein-2 - Pfizer/Astellas; InductOs; INFUSE Bone Graft; PF-5208771; rhBMP 2 - Pfizer/Astellas; rhBMP-2/CPM; YM 484

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Wyeth
  • Developer Medtronic Europe; Medtronic Sofamor Danek; Pfizer
  • Class Calcium regulators; Proteins
  • Mechanism of Action Osteogenesis stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Fracture; Intervertebral disc degeneration
  • Phase II Postmenopausal osteoporosis; Pseudoarthrosis
  • No development reported Bone disorders; Osteoarthritis
  • Discontinued Cancer

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Bone-disorders in Denmark (Implant, Controlled release)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Osteoarthritis in Denmark (Implant, Controlled release)
  • 01 Oct 2017 Medtronic completes a phase I trial for Osteoarthritis and Bone disorders in Denmark (NCT01690260)
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