Drug Profile


Alternative Names: Dexanabinone; ETS-2101; HU-211; PA-50211; PRS-211007; Sinnabidol

Latest Information Update: 27 Apr 2017

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At a glance

  • Originator Hebrew University of Jerusalem
  • Developer e-Therapeutics; Northern Institute for Cancer Research; Pharmos Corporation; University of California, San Diego
  • Class 3-ring heterocyclic compounds; Antineoplastics; Cannabinoids; Neuroprotectants; Small molecules
  • Mechanism of Action Apoptosis stimulants; NMDA receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Brain injuries
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Brain cancer; Solid tumours
  • Preclinical Malignant melanoma
  • Discontinued Brain injuries; Glaucoma; Mild cognitive impairment; Multiple sclerosis

Most Recent Events

  • 01 Apr 2017 Preclinical data in Solid tumours presented at the 108th Annual Meeting of the American Association for Cancer Research (AACR-2017)
  • 22 Mar 2016 e-Therapeutics completes a phase Ia trial for Brain cancer (Second-line therapy or greater) in USA (NCT01654497) prior to March 2016
  • 22 Mar 2016 e-Therapeutics completes a phase-I trial in Solid tumours in Poland, United Kingdom, Spain and Germany (IV) (NCT02423239) prior to March 2016
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