Complement C1 inhibitor protein - CSL Behring

Drug Profile

Complement C1 inhibitor protein - CSL Behring

Alternative Names: Berinert; Berinert HS; Berinert P; C1 esterase inhibitor - CSL Behring; C1 esterase inhibitor concentrate; C1 inaktivator HS; C1-INH - CSL Behring; CE 1145; Complement C1 inactivator - CSL Behring; CSL 830; Human C1 esterase inhibitor concentrate

Latest Information Update: 27 Mar 2017

Price : $50

At a glance

  • Originator CSL Behring
  • Class Complement C1 inactivator proteins; Vascular disorder therapies
  • Mechanism of Action Complement C1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Angioedema
  • New Molecular Entity No

Highest Development Phases

  • Marketed Hereditary angioedema
  • Phase I/II Transplant rejection
  • Discontinued Reperfusion injury; Septic shock; Vascular disorders

Most Recent Events

  • 22 Mar 2017 Efficacy data from the phase III COMPACT trial in Hereditary angioedema (SC), which met its primary endpoints, released by CSL Behring
  • 03 Mar 2017 Efficacy data from a subgroup analysis of the phase III COMPACT trial in Hereditary angioedema (SC) presented at the Annual Scientific Meeting of the American College of Allergy, Asthma & Immunology (AAAAI-2017)
  • 11 Nov 2016 CSL Behring plans a clinical trial for Reperfusion injury in Switzerland
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