Drug Profile


Alternative Names: Cosopt; Cosopt Mini; Cosopt PF; L-671152/timolol; MK-507/timolol

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Merck & Co; Merck Sharp & Dohme
  • Developer Akorn; Merck & Co; Merck Sharp & Dohme; Purdue Pharma; Santen Pharmaceutical; Sidus
  • Class Antiglaucomas; Propanolamines; Sulfonamides; Thiadiazoles; Thiophenes
  • Mechanism of Action Beta-adrenergic receptor antagonists; Carbonic anhydrase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Glaucoma; Ocular hypertension

Most Recent Events

  • 09 Dec 2015 COSOPT® licensed to Purdue Pharma in Canada
  • 10 Mar 2015 Japanese Ministry of Health, Labour and Welfare approves a preservative free formulation of dorzolamide/timolol for treatment of Glaucoma and Ocular hypertension in Japan
  • 15 Aug 2014 Santen Pharmaceutical files for approval of a preservative-free formulation of Dorzolamide/timolol in Japan
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