Drug Profile


Alternative Names: BCI-224; CEB 242; Memric; SB-202026

Latest Information Update: 23 Jul 2015

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At a glance

  • Originator GlaxoSmithKline
  • Developer BrainCells; GlaxoSmithKline
  • Class Antidepressants; Imines; Quinuclidines; Small molecules
  • Mechanism of Action Muscarinic M1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alzheimer's disease; Cognition disorders; Major depressive disorder; Schizophrenia; Type 2 diabetes mellitus

Most Recent Events

  • 14 Aug 2012 Proximagen has been acquired by Upsher-Smith
  • 26 Jun 2012 Sabcomeline is available for licensing as of 26 Jun 2012.
  • 19 Apr 2011 Phase-I clinical development in Cognition disorders in USA (unspecified route)
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