Drug Profile


Alternative Names: AP 1007; AP 1431; AP 1450; AP 1451; ISIS 2302

Latest Information Update: 15 Feb 2016

Price : $50

At a glance

  • Originator Isis Pharmaceuticals
  • Developer Atlantic Healthcare
  • Class Anti-inflammatories; Antipsoriatics; Antisense oligonucleotides; Thionucleotides
  • Mechanism of Action Intercellular adhesion molecule 1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pouchitis
  • New Molecular Entity Yes
  • Available For Licensing Yes - Pouchitis; Ulcerative colitis

Highest Development Phases

  • Phase III Pouchitis; Ulcerative colitis
  • No development reported Crohn's disease
  • Discontinued Asthma; Inflammation; Psoriasis; Renal transplant rejection; Rheumatoid arthritis

Most Recent Events

  • 11 Feb 2016 Phase-III clinical trials in Pouchitis in Canada (Topical)
  • 11 Feb 2016 Phase-III clinical trials in Pouchitis in Israel (Topical)
  • 11 Feb 2016 Atlantic Healthcare has patent-protection for alicaforsen
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