Palonosetron intravenous

Drug Profile

Palonosetron intravenous

Alternative Names: 2-QHBIQO; Aloxi Injection; Nuowei; ONICIT; Onicit; Palonosetron hydrochloride; Paloxi; RS-25259; RS-25259-197; RS-42358-197

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Roche Palo Alto LLC
  • Developer Helsinn; Taiho Pharmaceutical
  • Class Antiemetics; Isoquinolines; Quinuclidines; Small molecules
  • Mechanism of Action Serotonin 3 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Chemotherapy-induced nausea and vomiting; Postoperative nausea and vomiting

Most Recent Events

  • 15 Feb 2017 Palonosetron intravenous licensed to Mundipharma in Iran, Pakistan, Indonesia and 30 countries in Africa
  • 30 Jun 2016 Taiho Pharmaceuticals plans a phase III trial for Chemotherapy induced nausea and vomiting (In infants, In children, In adolescents) in Japan (JapicCTI-163305)
  • 09 Mar 2016 Helsinn completes a phase III trial in Chemotherapy induced nausea and vomiting in Hungary, Lithuania and Greece (IV, Infusion) (EudraCT2015-001747-37)
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