Drug Profile


Alternative Names: Pakio; RO 196327; Tempium

Latest Information Update: 24 Sep 1999

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At a glance

  • Originator Roche
  • Class Antiparkinsonians; Nootropics; Picolinic acids; Small molecules; Smoking cessation therapies
  • Mechanism of Action Antioxidants; Monoamine oxidase B inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Alzheimer's disease; Parkinson's disease; Smoking withdrawal

Most Recent Events

  • 24 Sep 1999 Discontinued-Clinical for Smoking withdrawal (PO)
  • 24 Sep 1999 Discontinued-I for Parkinson's disease in New Zealand (PO)
  • 24 Sep 1999 Discontinued-III for Alzheimer's disease in Europe (PO)
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