Drug Profile


Alternative Names: CGP 48664; CGP 48664A; SAM 486

Latest Information Update: 15 Jun 2009

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At a glance

  • Originator Novartis
  • Class Amidines; Antineoplastics; Indans
  • Mechanism of Action Adenosylmethionine decarboxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Cancer; Non-Hodgkin's lymphoma; Solid tumours

Most Recent Events

  • 06 May 2004 A study has been added to the adverse events and Cancer therapeutic trials sections
  • 27 Sep 2000 Phase-II clinical trials for Non-Hodgkin's lymphoma in USA (IV-infusion)
  • 27 Sep 2000 A phase II study in non-Hodgkin's lymphoma has been added to the therapeutic trials and adverse events sections
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