Drug Profile


Alternative Names: Biricodar dicitrate; Incel; VX 710; VX 710-3

Latest Information Update: 20 Jun 2007

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At a glance

  • Originator Vertex Pharmaceuticals
  • Class Chemosensitisers; Piperidines; Pyridines
  • Mechanism of Action P-glycoprotein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Bacterial infections; Breast cancer; Liver cancer; Ovarian cancer; Prostate cancer; Sarcoma; Small cell lung cancer

Most Recent Events

  • 18 Feb 2005 A preclinical study has been added to the Bacterial Infections pharmacodynamics section
  • 30 Nov 2004 Preclinical trials in Bacterial infections in USA (unspecified route)
  • 21 Jun 2001 Vertex is seeking collaborative partners to further develop and commercialise biricodar
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