Drug Profile


Alternative Names: Artist; Aucardic; BM 14190; Cardiol; Carloc; Caslot; Coreg; Coropres; Dilatrend; Dilbloc; Dimitone; DQ 2466; Eucardic; Kredex; Querto; SKF 105517

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Roche
  • Developer Columbia Northwest Pharmaceuticals; Daiichi Sankyo Company
  • Class Antihypertensives; Carbazoles; Ethanolamines; Heart failure therapies; Ischaemic heart disorder therapies; Phenyl ethers; Propanolamines; Small molecules
  • Mechanism of Action Alpha 1 adrenergic receptor antagonists; Antioxidants; Beta-adrenergic receptor antagonists; Calcium channel antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Angina pectoris; Heart failure; Hypertension
  • Phase III Atrial fibrillation
  • Discontinued Arrhythmias; Ischaemic heart disorders; Myocardial infarction; Post-traumatic stress disorders; Reperfusion injury

Most Recent Events

  • 25 Mar 2015 Ranbaxy Laboratories has been acquired by Sun Pharmaceutical Industries
  • 30 May 2013 Biomarkers information updated
  • 30 Sep 2011 Nycomed has been acquired by Takeda
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