AN 9

Drug Profile

AN 9

Alternative Names: Pivaloyloxymethyl Butyrate; Pivanex

Latest Information Update: 26 Mar 2007

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At a glance

  • Originator Bar-Ilan University
  • Class Antineoplastics; Butyrates; Butyric acids
  • Mechanism of Action Histone deacetylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Chronic lymphocytic leukaemia; Liver cancer; Malignant melanoma; Non-small cell lung cancer

Most Recent Events

  • 18 Mar 2005 Discontinued - Phase-II for Chronic lymphocytic leukaemia in USA (IV)
  • 18 Mar 2005 Discontinued - Phase-II for Malignant melanoma in USA (Topical)
  • 12 Jul 2004 AN 9 is available for licensing (
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