Pixantrone

Drug Profile

Pixantrone

Alternative Names: BBR-2278; BBR-2778; Pixantrone dimaleate; Pixuvri

Latest Information Update: 11 Jan 2017

Price : $50

At a glance

  • Originator University of Vermont
  • Developer Cell Therapeutics; CTI BioPharma
  • Class Anthracyclines; Anthraquinones; Antineoplastics; Isoquinolines; Small molecules
  • Mechanism of Action Alkylating agents; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Non-Hodgkin's lymphoma
  • Phase III Diffuse large B cell lymphoma; Follicular lymphoma
  • Phase I Cancer
  • Discontinued Breast cancer; Myasthenia gravis

Most Recent Events

  • 11 Jan 2017 Phase-III clinical trials in Diffuse large B cell lymphoma (Combination therapy, Second-line therapy or greater) in Slovakia, Russia, Romania, France, Denmark, Czech Republic, Bulgaria, Belgium and Austria (IV) before January 2017 (NCT01321541),
  • 11 Jan 2017 Phase-III clinical trials in Follicular lymphoma (Combination therapy, Second-line therapy or greater) in Slovakia, Russia, Romania, France, Denmark, Czech Republic, Bulgaria, Belgium and Austria (IV) before January 2017 (NCT01321541),
  • 01 Oct 2016 Phase-I clinical trials in Cancer (Monotherapy, Second-line therapy or greater, In infants, In children, In adolescents, In adults) in USA (IV) (NCT02800889)
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