Drug Profile


Alternative Names: Aptosyn; FGN 1™; Prevatac™; Sulindac sulfone

Latest Information Update: 18 Jun 2007

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At a glance

  • Originator OSI Pharmaceuticals
  • Class Antineoplastics; Small molecules; Sulfones
  • Mechanism of Action Angiogenesis inhibitors; Apoptosis stimulants; Cyclic GMP phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Familial adenomatous polyposis; Non-small cell lung cancer; Prostate cancer; Small cell lung cancer

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 18 Jun 2004 Data from a media release have been added to the Cancer therapeutic trials section
  • 12 May 2004 Phase-III clinical trials in Prostate cancer in Canada (PO)
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