Drug Profile


Alternative Names: Bredinin; HE-69

Latest Information Update: 06 Feb 2017

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At a glance

  • Originator Asahi Kasei
  • Developer Asahi Kasei; Asahi Kasei Pharma Corp; Chong Kun Dang
  • Class Antirheumatics; Ribonucleosides; Small molecules
  • Mechanism of Action Immunosuppressants; Inosine monophosphate dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Lupus nephritis; Nephrotic syndrome; Renal transplant rejection; Rheumatoid arthritis

Most Recent Events

  • 06 Feb 2017 Mizoribine is still in phase III trials for Nephrotic syndrome (Treatment-resistant) and Lupus nephritis in China (PO)
  • 01 Nov 2014 Phase-III clinical trials in Lupus nephritis in China (PO) (NCT02256150)
  • 01 Nov 2014 Phase-III clinical trials in Nephrotic syndrome (Treatment-resistant) in China (PO) (NCT02257697)
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