Antithymocyte globulin

Drug Profile

Antithymocyte globulin

Alternative Names: Antithymocyte immunoglobulin; Polyclonal rabbit antithymocyte globulin; Rabbit antithymocyte globulin; rATG; Thymoglobulin; Thymoglobuline

Latest Information Update: 26 Apr 2017

Price : $50

At a glance

  • Originator sanofi pasteur
  • Developer Genzyme Corporation; National Institute of Diabetes and Digestive and Kidney Diseases; Sanofi Genzyme; Sanofi Pasteur; University of Texas M. D. Anderson Cancer Center; Virginia Commonwealth University
  • Class Polyclonal antibodies
  • Mechanism of Action Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myelodysplastic syndromes
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Aplastic anaemia; Bone marrow transplant rejection; Graft-versus-host disease; Liver transplant rejection; Pancreas transplant rejection; Renal transplant rejection; Transplant rejection
  • Phase II Myelodysplastic syndromes; Type 1 diabetes mellitus

Most Recent Events

  • 25 Apr 2017 Launched for Renal transplant rejection (Prevention) in USA (IV)
  • 24 Apr 2017 Registered for Renal transplant rejection (Prevention) in USA (IV)
  • 01 Dec 2015 Genzyme completes a phase-III trial in Graft-versus-host disease in Canada (ISRCTN29899028)
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