Drug Profile


Alternative Names: AL-38583; Ariflo; SB 207499; SKB 207499

Latest Information Update: 14 Mar 2012

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At a glance

  • Originator GlaxoSmithKline
  • Developer Alcon; GlaxoSmithKline
  • Class Antibronchitics; Carboxylic acids; Nitriles; Small molecules
  • Mechanism of Action Type 4 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Asthma; Chronic obstructive pulmonary disease; Dry eyes; Ocular inflammation

Most Recent Events

  • 14 Mar 2012 Discontinued - Phase-II for Dry eyes in USA (Ophthalmic)
  • 14 Mar 2012 Discontinued - Phase-II for Ocular inflammation in USA (Ophthalmic)
  • 14 Mar 2012 Discontinued - Phase-III for Chronic obstructive pulmonary disease in USA (PO)
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