Rebamipide

Drug Profile

Rebamipide

Alternative Names: Mucosta; OPC-12759; OPC-12759E; OPC759; Ophthalmic rebamipide; Pramipide; Proamipide; Rebamipide eyedrops

Latest Information Update: 15 Dec 2016

Price : $50

At a glance

  • Originator Otsuka Pharmaceutical
  • Developer Acucela; Otsuka Pharmaceutical
  • Class Amino acids; Antiulcers; Cytoprotectives; Quinolones; Small molecules
  • Mechanism of Action Mucin stimulants; Oxygen radical formation antagonists; Prostaglandin agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Dry eyes; Gastric ulcer; Gastritis
  • Phase II Stomatitis
  • Discontinued Cancer; Diabetes mellitus; Keratoconjunctivitis; NSAID-induced ulcer; Ulcerative colitis; Xerostomia

Most Recent Events

  • 10 Jun 2016 Otsuka Pharmaceutical initiates a clinical pharmacological trial for Dry eyes in Japan (Ophthalmic) (UMIN000022629)
  • 06 Jun 2016 Otsuka Pharmaceutical plans a clinical pharmacological trial for Dry eyes in Japan (Ophthalmic) (UMIN000022629)
  • 17 Dec 2014 Phase-II clinical trials in Dry eyes (Neoadjuvant therapy) in Japan (Ophthalmic) (UMIN000016986)
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